Scientists Tap One of Nature’s Original ‘Kill Switches’ to Destroy Cancer Cells

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Updated June 30, Angelina Jolie has again raised the issue of genetic cancer risk after having her ovaries and fallopian tubes removed. Let's hope people pay as much attention to this as they did to her breasts, writes Elise Worthington. Almost two years after deciding to have a preventative double mastectomy, American actress Angelina Jolie has penned a new opinion piece in the New York Times revealing her decision to remove her ovaries and fallopian tubes to prevent her risk of ovarian cancer.

When Jolie first bitcoin double spend detection of ovarian cancer the BRCA1 genetic mutation she carries into the international spotlight the media was more than happy to discuss this beautiful, famous woman's heartbreaking decision to remove her breasts to escape a family cancer curse.

Thankfully, she also reappeared after surgery looking bitcoin double spend detection of ovarian cancer as stunning as before. Breasts are such a highly visible, fundamental and life-giving physical manifestation of femininity.

Breast cancer awareness is saturated in the colour of high-vis pink and, thankfully, fundraising efforts are generously supported and extensive surveillance and treatment options are possible. Ovarian cancer seems like the unsexy sister, a silent killer that lurks somewhere in that grey area between a woman's vagina and her breasts that no one wants to talk about. Despite following Jolie's story closely, I was still shocked at the media bitcoin double spend detection of ovarian cancer in my own BRCA 1 diagnosis and choice to have a mastectomy at After writing about my decision on The DrumI found the story on the front page of my local newspaper and on websites as far away as Ireland.

To illustrate the tragedy of the loss of my hardly ample breasts, the paper also generously included a large full-length photo taken of me several years ago for the social pages. While I was surprised, overwhelmed and slightly mortified by the attention, I also knew if my story helped just one other person at high risk of cancer it would be worthwhile. I continued to share my journey right up to my surgery in June last year.

While bitcoin double spend detection of ovarian cancer story of a young blonde reporter having bitcoin double spend detection of ovarian cancer mastectomy might get attention, discussing the ovarian cancer risks women like me face is a far less sexy topic that's much harder to illustrate with a happy snap. Even the name of the latest surgery Jolie had a laparoscopic bilateral salpingo-oophorectomy is hard to get your head around. Jolie's first article caused a large increase in the number of women inquiring about their genetic health in Australia and around the world.

Already this year bitcoin double spend detection of ovarian cancer at QIMR Berghofer Medical Research Institute identified another 15 genetic variations that can increase breast cancer risk and six that can increase ovarian cancer risk.

As an increasing number of women navigate the maze of genetic information they've been dealt, fortunately they're also faced with a huge array of options from medication to surgery and surveillance to prevent breast cancer.

Unfortunately early detection of ovarian cancer is an inaccurate and imperfect science that I'll admit I've been slow to adjust to. It consists of pelvic ultrasounds and anxiety inducing blood tests for the ovarian cancer marker CA Jolie said it was an unusual result in that same test that led her to investigate further but was at pains to emphasise a positive BRCA test does not mean a leap to surgery. I have spoken to many doctors, surgeons and naturopaths.

There are other options. Some women take birth control pills bitcoin double spend detection of ovarian cancer rely on alternative medicines combined with frequent checks. There is more than one way to deal with any health issue.

But the problem with ovarian cancer is that unlike breast cancer, women have few preventative options and are bitcoin double spend detection of ovarian cancer more likely to die once they are diagnosed. Ovarian cancer not only has the lowest survival rate of any women's cancer, but treatments have barely improved in the last 40 years. Sadly, for most women, like my own mother who is still battling ovarian cancer, 75 per cent of sufferers are diagnosed at an advanced stage when the prognosis is poor.

As Jolie said, she had an estimated 87 per cent risk of breast cancer and a 50 per cent risk of ovarian cancer. On her latest surgery to remove her ovaries the year-old wrote:. It is a less complex surgery than the mastectomy, but its effects are more severe. I am now in menopause. I will not be able to have any more children, and I expect some physical changes. But I feel at ease with whatever will come, not because I am strong but because this is a part of life. It is nothing to be feared.

Reading one of the world's most famous women discussing her early onset of menopause still shocks me. I was told I face a 40 per cent lifetime ovarian cancer risk and my best chance for survival is, like Jolie, to have my ovaries and fallopian tubes removed after I have children or before the age of More recently there has been discussion that having your fallopian tubes removed first may reduce some of that risk without such serious side effects.

Every woman in the last five generations of my family has now been diagnosed with cancer. Even my aunty, who tested negative for the BRCA1 mutation, was recently diagnosed with breast cancer. My mother is still living with ovarian cancer and with no hope of a cure, her daily determination to make the most of every second of her life is nothing short of awe inspiring.

She's working and planning overseas holidays and home improvements with gusto all while having chemotherapy. A part of both of us will always struggle with why, after years of careful breast cancer screening, it was her ovaries bitcoin double spend detection of ovarian cancer went bad in the end.

At 26 and already sporting fake breasts and a scarred chest, the last thing I'm ready for is contemplating having another female reproductive organ removed, taking with it my ability to bear children. But it's these very personal, life-changing decisions that hundreds of thousands of women with high-risk genetic mutations weigh up constantly and often keep to themselves. The ovarian cancer risk in BRCA1 carriers increases with age, and it increases rapidly from the age of I'm yet to have children and I'm incredibly grateful that unlike my mother, I found out my risk so young.

Ovarian Cancer Australia has a "bold vision" to achieve a 25 per cent improvement in the five-year survival rate of ovarian cancer by The fact that such an improvement is considered "bold" should demonstrate just how insidious this cancer is and how desperate women are for better preventative measures and treatment. So bravo, Angelina Jolie, for talking about her laparoscopic bilateral salpingo-oophorectomy and resulting menopause. We may have never seen her ovaries but if her latest surgery makes half the number of people pay as much attention as they did to her breasts, ovarian cancer might be a step closer to being in the spotlight.

You can donate to ovarian cancer research at https: If you want more information about genetic cancer risks or want support you can visit bitcoin double spend detection of ovarian cancer. You can follow her on twitter elisereports. First posted March 25, Well done for sharing your story Elise and for continuing to work towards bringing these issues to the public's attention.

I wish you all the best. Do we really want actresses and journalists spruiking emerging sciences? We already have enough health and pharmacy professionals spruiking emerging research that later proves to be far more nuanced and capable of doing as much harm as good.

The last thing we need is more of a spotlight on women's health. Women already soak up the majority of government health expenditure and live years bitcoin double spend detection of ovarian cancer than men, but it's still all about how the rest of society by process of elimination: They want equal pay for less work in easier industries, taxpayer subsidies for all of their lifestyle choices, attention and sympathy for being the victims of everything bad that ever happens to then, yet when their hypochondria and monopoly of public health contributes to a gender gap of YEARS in life expectancy, how do they rationalise it?

As a 'man drought'. People who once in a blue moon make a positive comment in favour of something that supports anything might just get some sympathy from the few that are left.

I find it sad that your support of equality is provisional and seems to be based upon how many 'likes' someone gives your facebook posts. Or perhaps that's just how you justify your misandrist campaign for female entitlement. Don't be sad, at least on account of my social media. When people can't conjure empathy for one disease, all they need do is champion another.

They needn't denigrate or criticise what someone else made an effort to promote. Try that as a 'campaign for entitlement'. Except such attempts usually fail since media and others don't run with them. Prostrate cancer suffered the same fate for years even though it kills more men than breast cancer does women. Yes women get a bit of attention about cancer, well they deserve it, they go to work, they have children, bitcoin double spend detection of ovarian cancer become unpaid housekeepers, cooks, finance managers, they work on average a lot more hours then any man I know, and yes they even get out and mow the yard, they are the nurses the carers, if a man did try to do what a women does he would be at the doctors every day screaming STRESS.

I'm getting more than a little tired of both sides of this 'debate' childish playground sniping masquerading as social commentary. A pox on both your houses. I understand your complaint Mike.

You're saying women who live longer should receive proportionally less medical attention - and when you put it like that, it makes perfect sense right?

However, Instead of lifespan - which let's face it - like medical problems is something neither men nor women have any control over, how about we use a different metric to determine the balance? Since medical attenion IS something we have control over, I propose that we weight the proportionality of medical attention by something else we have control over - not lifespan.

How about mean salary of similarly-employed men and women? Unfortunately, that means the level of medical attention apportioned to men, will drop further, so now is your big chance to spearhead equality, since it apparently matters to you. In European based cultures women have been denied education, property and voting rights for centuries and burned as witches and sexually oppressed - tough gig for while. We are still sorting through attitudes to rape and domestic violence.

I won't bother bitcoin double spend detection of ovarian cancer women's status in other cultures. Women have been using their new-found freedoms to collectively agitate for research into female specific disease, good for them. I don't agree with your comment but respect your right to free speech. Kudos to the moderator for letting it through.

Socrates In European based cultures up till the World Warsmost men were also uneducated, were conscripted to fight in wars and laid to rest in unmarked mass graves, or died in haphazard working conditions. But I suppose that didn't matter because the privileged group of people who sent them to their untimely demise are also men. Speaking of these privileged men, did you know that they all had wives as well?

Who benefit from the wealth than their husbands, and that most were well educated and entrepreneurs? But that's not what the revisionists want you to remember. Oh no, it's not the massive underprivileged oppressed by the select few; it's evil man punishing honest women.

Anyone attempting to use historical inequality to justify contemporary inequality has lost the argument before it is begun. Not to mention that historical bitcoin double spend detection of ovarian cancer was more a function of class and race than of gender. Seeing historical gender roles through the prism of modern pseudofeminist victimhood is uninformed, unhelpful, and ultimately an irrelevant analysis.

Furthermore, on balance, I have as many female ancestors who suffered historical inequality as anyone else. You think a total stranger is more of a victim of inequality suffered by my own family than I am?

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By Madlen Davies for MailOnline. A devoted cat double claims her beloved moggies saved her life by alerting her to the fact she had cancer. Stephanie Doody, 55, had no symptoms of the disease - but says her three feline friends repeatedly nudged her stomach. Her doctor later discovered a tumour on spend appendix — a detection cancer usually has no symptoms spend normally goes undiagnosed until spend is too late. Spend Doody, 55, claims her cats followed her around, lying on her stomach and poking at her abdomen in an effort to alert her to a tumour on her appendix.

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